Figure 5

(A) Time-resolved temperature in the irradiated nude mouse skins during 10 min irradiation of 980- and 800-nm laser as a function of different power density.(B) The decay of excitation power as a function of the penetration depth of tissues. (C) Merged bright-field images with NIR-to-NIR DC emission of NaGdF4:Nd/NaYF4/NaGdF4:Nd,Yb,Er/NaYF4 NCs under 800-nm excitation (top row) and UC emission of traditional NaGdF4:Yb,Tm/NaYF4 NCs under 980-nm excitation (bottom row). Intensities of the signals were also summarized in it. All images were acquired under the same instrumental conditions (power density 1 W/cm2). (D) In-vivo imaging of a nude mouse from the chest side (left) and the back side (right) by imbuing the water soluble NaGdF4:Nd/NaYF4/NaGdF4:Nd,Yb,Er/NaYF4 NCs to stomach.