Figure 3
From: Tungsten Oxide Nanorods: An Efficient Nanoplatform for Tumor CT Imaging and Photothermal Therapy
Photothermal ablation of HeLa cells in vitro using PEGylated WO2.9 NRs under 980 nm laser irradiation.
Optical images stained by trypan blue (a) and confocal fluorescence images stained by Calcein AM/PI (b). (a1) and (b1), control HeLa cells without treatment. (a2) and (b2), HeLa cells treated with the 980 nm laser irradiation for 8 min (0.35 W/cm2) in the absence of PEGylated WO2.9 NRs. (a3) and (b3), HeLa cells incubated with PEGylated WO2.9 NRs (50 μg/mL) without laser irradiation. (a4) and (b4), HeLa cells incubated with PEGylated WO2.9 NRs (50 μg/mL) under the 980 nm laser irradiation for 8 min (0.35 W/cm2). (c) Cell viability determined by FACS and MTT assay (inset) under different concentrations of PEGylated WO2.9 NRs with (red) or without (blue) the 980 nm laser irradiation for 8 min (0.35 W/cm2). (d) Cell viability determined by FACS and MTT assay (inset): cells were treated with 980 nm laser irradiation at different power density for 8 min with (red) or without (black) PEGylated WO2.9 NRs (50 μg/mL).
