Figure 4
From: Tungsten Oxide Nanorods: An Efficient Nanoplatform for Tumor CT Imaging and Photothermal Therapy
The mechanism of photothermal ablation of HeLa cells using PEGylated WO2.9 NRs determined by FACS with 980 nm laser irradiation.
Representative FACS plots. (a1), control HeLa cells without treatment. (a2), HeLa cells incubated with 50 μg/mL PEGylated WO2.9 NPs without laser irradiation. (a3), HeLa cells after 980 nm laser irradiation for 8 min (0.30 W/cm2) in the absence of PEGylated WO2.9 NRs. (a4), HeLa cells incubated with 50 μg/mL PEGylated WO2.9 NPs after 980 nm laser irradiation for 8 min (0.30 W/cm2). (b) apoptosis rate of HeLa cells incubated with (black) or without (red) PEGylated WO2.9 NPs (50 μg/mL) at different power density of 980 nm laser irradiation for 8 min. (c) apoptosis and necrosis rate of HeLa cells incubated with different concentrations of PEGylated WO2.9 NPs with (orange and green bars) or without (white and grey bars) 980 nm laser irradiation for 8 min (0.35 W/cm2).
