Table 1 Thermokinetic characteristics of R. coptidis (200 μg/mL) and samples containing different concentrations of BER on S. dysenteriae growth at 37°C (n = 3, Mean ± SD)

C (μg/mL)	k₁ (min⁻¹)	k₂ (min⁻¹)	t₁ (min)	p₁ (μW)	t₂ (min)	p₂ (μW)	I (%)	P (U/g)	W (%)
Control	0.107 ± 0.011	0.021 ± 0.007	74.0 ± 1.1	369.2 ± 2.1	152.0 ± 1.6	467.0 ± 3.0	0.00	–	–
R. coptidis	0.090 ± 0.008	0.017 ± 0.003	76.0 ± 1.2	371.4 ± 2.3	170.3 ± 1.9	359.4 ± 3.7	16.38	–	–
0^§	0.109 ± 0.010	0.020 ± 0.002	77.3 ± 0.6	408.4 ± 1.5	161.0 ± 1.4	455.2 ± 3.5	5.51	–	0.00
15^§	0.097 ± 0.005	0.018 ± 0.003	74.7 ± 0.5	358.0 ± 2.6	166.3 ± 1.3	391.1 ± 3.2	9.65	27.6	8.08
45^§	0.082 ± 0.009	0.015 ± 0.004	80.0 ± 0.9	395.5 ± 2.8	189.0 ± 1.9	320.2 ± 2.9	28.23	50.5	20.87
60^§	0.079 ± 0.007	0.011 ± 0.003	88.0 ± 1.3	258.1 ± 2.0	271.3 ± 2.3	136.1 ± 1.3	45.73	67.0	26.02
80^§	0.032 ± 0.004	0.005 ± 0.002	114.0 ± 1.4	170.8 ± 1.6	424.3 ± 3.2	111.1 ± 2.2	82.55	96.3	31.92
120^§	0.023 ± 0.005	0.003 ± 0.001	424.3 ± 2.1	268.5 ± 2.4	185.0 ± 2.9	81.7 ± 2.1	97.32	76.5	41.29

C: concentration (μg/mL), k₁ and k₂: the growth rate constants in the first and second exponential phases, t₁ and t₂: the appearance time of the first and second highest peaks, p₁ and p₂: the heat flow power (HFP) of the first and the second highest peaks, I: inhibition ratio in stage k₂, P: relative potency of BER, W: content of BER in the added sample, W = W_BER/(W_BER + W_BER⁻) × 100%, where W_BER is the added weight of BER, W_BER⁻ is the weight of R. coptidis extract (200 μg/mL) with BER removed [W_BER⁻ = (1–the content of BER in the R. coptidis extract) × 200 μg/mL]. ^§Concentration of BER in the negative sample. The above measurements were performed in triplicate and error bars represent standard error of the mean.

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