Figure 3
From: Network Understanding of Herb Medicine via Rapid Identification of Ingredient-Target Interactions
The diagram of possible molecular mechanism underlying Yadanzi's anti-NSCLC activity.
The square stands for the putative target protein of Yadanzi ingredients predicted in this study (the proteins which targeted by equal to or more than 10 ingredients are marked gray). The thicker protein block indicates at least one ingredient-target interaction has been validated by previous experimental evidences or computational simulation in this study. The diamond stands for ingredient and the number in the diamond is the number of ingredients binding to the corresponding protein. The actions (inhibition of activation) of ingredient-protein interactions were determined by comparative docking analysis.
