Figure 1 | Scientific Reports

Figure 1

From: Differential effects of propranolol on conditioned hyperactivity and locomotor sensitization induced by morphine in rats

Figure 1

Induction of conditioned hyperactivity and locomotor sensitization.

Rats were put into locomotion chambers for 20 min (paired with CS) with an injection of 5 mg/kg morphine (Mor group) or saline (Sal group) afterwards. The locomotor activity was recorded for another 120 min. This session was conducted during seven consecutive days (days 1–7). (A) Locomotor activity collected during the 20-min period prior to drug injection; (B) Locomotor activity collected during the 120-min period after morphine injection. Note that the statistical significance was not shown on Fig. 1B for the group comparisons because Mor-R-Sal, Mor-R-Pro and Mor-NR-Pro groups were all significantly higher than Sal group throughout the seven days.

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