Table 2 The main pharmacokinetic moment parameters of MGN
From: Perturbation of mitiglinide metabolism by chronic unpredicted mild stress in rats
Parameter | Control group (n = 9) | Depression group (n = 9) | |
|---|---|---|---|
Cmax | ug/mL | 1.88 ± 0.23 | 1.84 ± 0.93 |
Tmax | min | 23.00 ± 25.30 | 22.22 ± 14.17 |
AUC(0–∞) | ug/mL*min | 501.79 ± 68.24 | 475.16 ± 62.01* |
MRT(0–∞) | min | 367.02 ± 85.84 | 245.95 ± 68.83* |
t1/2z | min | 256.12 ± 48.50 | 168.10 ± 34.68* |
CLz/F | mL/min | 0.83 ± 0.08 | 0.96 ± 0.11* |
