Figure 1
From: Wharton's Jelly human Mesenchymal Stem Cell contact guidance by noisy nanotopographies

Substrates morphological characterization.
(a) Scheme of the nanoimprint process. (b–f) Replica scheme and scanning electron microscope images of noisy COC-NGs (500-nm ridge- and groove-width). In SEM images, dark and bright areas correspond to groove and ridge, respectively. Each substrate is defined by the percentage of noise and a cell-dependent directionality (δ). Negative noise on COC replicas consists of links between adjacent ridges. Scale bar = 2 μm.