Figure 3
From: Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer
Overexpression of Hes1 in colon cancer cell lines induces stem-like cellular marker alterations.
(A) qRT-PCR demonstrates an increased expression of Hes1, CD133, ABCG2, Nanog, ALDH1, CD44 and Bmi-1 in Hes1-expressing (LV-Hes1) cells in comparison with the vector control (LV-con). (B) Western blot reveals an increased expression of Hes1, CD133, ABCG2, Nanog, ALDH1 in Hes1-expressing cells.
