Figure 7

MMP-2 activation Inhibition by α1(IV)NC1 without affecting K-1-3 and MMP-9.
(a) Angiostatin generation in wild type and α1-integrin null tumor bearing mice plasma (upper) and coomassie stained gel with equal loading of the plasma used for western blot (lower). (b) MMP-9 and MMP-2 activity in gelatin zymography of plasma from wild type and α1-integrin null tumor bearing mice.