Figure 1 | Scientific Reports

Figure 1

From: STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells

Figure 1

Short exposure to KSHV induces STAT3 activation in human DCs.

DCs were mock treated or exposed to (A) active or (B) UV-inactivated virus (UV-KSHV) for 15 and 30 min and STAT3, NF-kB p65 and AKT phosphorylation were analysed by western blot. Total STAT3, NF-kB p65, AKT are also shown. STAT3, NF-kB p65 and AKT phosphorylation and their fold of induction, based on densitometric analysis of the ratio of phospho/total molecules, are shown. GAPDH was included as protein loading control. 1 × 106 overnight serum-starved DCs/point were used in all experiments. One representative experiment out of three is shown.

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