Figure 7 | Scientific Reports

Figure 7

From: Nitric Oxide Inhibits Hetero-adhesion of Cancer Cells to Endothelial Cells: Restraining Circulating Tumor Cells from Initiating Metastatic Cascade

Figure 7

NO scavenger Hb reversed the inhibitory effect of CAP-NO on the hetero-adhesion between HT-29 and HUVECs and -induced expression of VCAM-1 in the presence of IL-1β (1 ng/mL).

(a) 5-min pretreatment with Hb (1 μM) reversed the inhibition CAP-NO on the IL-1β-induced adhesion determined by fluorescence-labeled cell count assay. (b) Hb also reversed IL-1β-induced expression of VCAM-1 (CD106). Results are expressed as the mean fluorescence intensities and calculated as percentage of controls (IL-1β only). Bars represent the mean ± SEM (n = 3).

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