Figure 1

Schematic illustration of forming bioactive mesoporous composite by (I) covalently attaching polymerizable groups on an enzyme molecule by acrylation, (II) wrapping the modified protein molecule (core) with a poly(acrylamide) shell via in-situ polymerization and (III) encapsulating enzyme nanocapsules inside the cavities of hierarchically mesoporous silica through physical adsorption.