Figure 3

Co-localization of p62 and PrP after proteasome inhibition.
(a) Total PrP (SAF32: green) and p62 (red) were visualized in N2a58 and ScN2a58 cells with (+) or without (−) MG132 (10 μM, 24 h). Bars: 20 μm. (b) After the treatment of guanidine thiocyanate, PrPSc (SAF61: green) and p62 (red) were visualized in N2a58 and ScN2a58 cells with (+) or without (−) MG132 (10 μM, 24 h). Bars: 20 μm.