Figure 4
From: miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction
miR-34c decreased fibrotic area in UUO kidneys.
(A) Hematoxylin-Eosin stain of kidneys with ureteral obstruction under administration of miR-34c or sham. Scale bars were indicated at the lower right corner of the pictures. (B) Masson trichrome stain of kidneys with ureteral obstruction under administration of miR-34c or sham. Scale bars were indicated at the lower right corner of the pictures. Additional pictures are available in Supplementary Fig. S5. (C) A graph showing the percent of fibrosis area in Masson trichrome stain samples. Quantification was done using ImageJ. (D) Immunohistochemistry showing α-SMA (green), KSP (red) and DAPI (blue) in kidneys with or without ureteral obstruction under administration of miR-34c or sham. Scale bars were indicated at the lower right corner of the pictures. (E) A graph showing the percent of α-SMA positive area. (F) A graph showing the percent of KSP positive area.
