Figure 5
From: miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction
miR-34c attenuated kidney fibrosis in UUO mice.
Real-time PCR of connective tissue growth factor (CTGF), alpha-smooth muscle actin (α-SMA), collagen type 1 (Col1a1), collagen type 3 (Col3a1), fibronectin (Fn1) and hairy/enhancer-of-split related with YRPW motif-like (HeyL). Normal right: right kidneys of sham-operated mice (n = 3), Normal left: left kidneys of sham-operated mice (n = 3), Sham control: contralateral kidneys of sham-injected mice with UUO (n = 5), miR-34c control: contralateral kidneys of miR-34c injected mice with UUO (n = 4), Sham obstructed: UUO kidneys of sham-injected mice (n = 5), miR-34c obstructed, UUO kidneys of miR-34c injected mice (n = 4).
