Figure 7 | Scientific Reports

Figure 7

From: Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism

Figure 7

The molecular mechanism of DHM-induced liver cancer cell growth regression and apoptosis.

The AKT pathway was inhibited by DHM treatment and Bad phosphorylation was reduced, which resulted in tumor cell apoptosis. In addition, tumor cell growth regression and apoptosis resulted from the transcriptional activation of the P21 and BAK genes in a p53-dependent manner.

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