Table 1 Linear regression for fetal and infant growth variables and BHR

	Unadjusted analysis				Adjusted analysis
	Beta	95% CI	P-value	n	Beta	95% CI	P-value	n
Birthweight	−0.040	−0.400 to 0.319	0.83	225	−0.051	−0.408 to 0.307	0.78	224
Head circumference at birth	−0.001	−0.362 to 0.359	0.99	225	−0.017	−0.376 to 0.341	0.92	224
Abdominal circumference at birth	0.108	−0.261 to 0.478	0.56	225	0.134	−0.239 to 0.506	0.48	221
Head circumference growth between 11 and 19 weeks' gestation	−0.152	−0.678 to 0.374	0.57	114	−0.224	−0.726 to 0.279	0.38	113
Abdominal circumference growth between 11 and 19 weeks' gestation	0.490	−0.138 to 1.119	0.13	110	0.643	0.038 to 1.247	0.037	109
Head circumference growth between 19 and 34 weeks' gestation	−0.066	−0.410 to 0.278	0.71	216	−0.050	−0.393 to 0.293	0.77	213
Abdominal circumference growth between 19 and 34 weeks' gestation	0.131	−0.199 to 0.461	0.43	224	0.246	−0.095 to 0.584	0.15	221

Measurements of circumferential growth were calculated as the conditional change in the relevant circumference between either 11 and 19 or 19 and 34 weeks' gestation conditional on either 11 or 19 week circumference respectively. Measurements were corrected for regression to the mean and exact age at measurement Not all women were scanned at each time point and positioning of the fetus occasionally precluded some measurements. If identified as a likely confounder in the multivariate model, the following were adjusted for: maternal history of asthma, eczema, rhinitis or atopy; paternal history of asthma, eczema or rhinitis; maternal age, body mass index, height, smoking in pregnancy, educational achievement and parity; child's gender and parental social class.

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