Figure 6
From: 2′-Epi-uscharin from the Latex of Calotropis gigantea with HIF-1 Inhibitory Activity

Inhibition of the hypoxia-induced HIF-1 transcriptional activity of uscharin (1), 2′-epi-uscharin (2) and digoxin by using a T47D cell-based HRE-luciferase reporter assay.