Figure 5

Effect of oral administration of P. gingivalis on the gene and protein expressions in liver.
(a) Comparison of relative gene expression levels in the liver tissue between the P. gingivalis-administered and the sham-administered mice (N = 8 in each group). The relative quantity of experimental mRNA was normalized to the relative quantity of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA. (b) TNF-α levels in the liver tissue were determined by ELISA of tissue lysates. All data are means ± SD. (*p < 0.05; **p < 0.01; ***p < 0.001, Mann-Whitney U-test).