Table 5 Characteristics of the studies selected in the meta-analysis

From: MDM2 SNP309 polymorphism is associated with colorectal cancer risk

Author

Years

Country

Ethnicity

Genotying methods

Source of controls

Sample size (cases/controls)

Cases (TT/TG/GG)

Controls (TT/TG/GG)

Alhopuro

2005

Finland

European

PCR-RFLP

Population

969/185

334/465/170

56/98/31

Sotamaa

2005

Finland

European

PCR-RFLP

Population

121/209

38/66/17

78/94/37

 

2005

United States

European

PCR-RFLP

Population

30/118

15/11/4

45/52/21

Menin

2006

Italy

European

PCR-RFLP

Population

153/92

69/70/14

40/40/12

Talseth

2006

Australia and Poland

European

TaqMan PCR

Hospital

116/98

45/57/14

40/51/7

Alazzouzi

2007

Spain

European

PCR-SSCP

Hospital

152/184

66/69/17

97/63/24

Chen

2009

China

Asian

PCR-CE

Population

123/138

27/66/30

29/83/26

Sugano

2010

Japan

Asian

LH-MSAs

Population

211/59

61/95/55

12/27/20

Joshi

2011

Japan

Asian

PCR-RFLP

Population

685/778

129/373/183

177/384/217

Chaar

2012

Tunisia

European

PCR-RFLP

Population

167/167

11/86/70

64/56/47

Zhang

2012

China

Asian

MALDI-TOF MS

Hospital

444/569

131/223/90

180/281/108

  1. PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; SSCP, single-stranded conformation polymorphism; CE, capillary electrophoresis; LH-MSAs, Loop-hybrid mobility shift assay; MALDI-TOF MS, Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.