Table 1 Demographic and background data of patients and controls

From: Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement

Explaination of subjects

Group 1 (KPUM)

Group 2 (NIHS)

a

Number of SJS/TEN patients with SOC who had taken cold medicines for treatment of common cold (CM-SJS/TEN with SOC group)

131

20

 

Female/Male

80/51

14/6

 

Age of onset (years, mean ± SD)

26.6 ± 17.5

54.0 ± 17.7

b (which are included in a)

Number of SJS/TEN patients with SOC who had taken acetaminophen for treatment of common cold (Acetaminophen-SJS/TEN with SOC group)

(59)

(14)

 

Female/Male

37/22

9/5

 

Age of onset (years, mean ± SD)

31.1 ± 15.8

35.2 ± 16.9

c

Patients with SJS/TEN without SOC who had taken cold medicines for treatment of common cold (CM-SJS/TEN without SOC group)

 

16

 

Female/Male

-

9/7

 

Age of onset (years, mean ± SD)

 

62.0 ± 25.0

d

Patients with SJS/TEN with SOC who had taken medicines not for treatment of common cold (CM unrelated-SJS/TEN with SOC group)

14

38

 

Female/Male

11/3

19/19

 

Age of onset (years, mean ± SD)

44.8 ± 19.3

57.4 ± 23.1

the samples excluded because of drug unrelated or detail unknown

17

-

total number of the SJS/TENpatients

162

74

Controls

Healthy volunteers

419

220

 

Female/Male

350/69

131/89

 

Age (years, mean ± SD)

-

35.5 ± 11.0

  1. CM-SJS/TEN: Cold medicine-related SJS/TEN.
  2. SOC: severe ocular surface complications.
  3. KPUM: Kyoto Prefectural University of Medicine, NIHS: National Institute of Health Sciences.