Figure 3

NMR analysis of MBD1-c.

(A) NOE connectivity plot of MBD1-c. The bar thickness reflects of the relative inter-proton distance. A thicker bar denotes a closer inter-proton distance. (B) Traditional chemical shift index (CSI) plot based on Δ(C_α − C_β) = (C_{α, MBD1-c} − C_{α, random coil} − C_{β, MBD1-c} − C_{β, random coil}). The residues are numbered according to MBD1 isoform 1^44,45. (C) The CD spectra of MBD1-c.