Figure 4 | Scientific Reports

Figure 4

From: Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans

Figure 4

Transcription factor activity and targets in up-regulated genes.

(A) shows the transcript abundance of the four transcription factors enriched for targets among the up-regulated genes in bar-1(ga80). The fold-change in bar-1/N2 is shown. The levels of pqm-1, pha-4 and mdl-1 are significantly higher in bar-1(ga80) (linear model, p < 0.01), whereas this is not the case for elt-3 (linear model, p = 0.158). (B) A Venn-diagram of the up-regulated genes associated with the four enriched transcription factors. There is a high level of overlap between the associations as >50% of the targets are associated with multiple transcription factors.

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