Figure 1

Synthesis of di-amine derivatives of UA.
Reagents and conditions include (a) anhydride/pyr/DMAP, R.T.; (b) (CO)2Cl, CH2Cl2, R.T.; (c) di-amine, CH2Cl2, R.T.; and (d) NaOH, CH3OH/THF, R.T.
Synthesis of di-amine derivatives of UA.
Reagents and conditions include (a) anhydride/pyr/DMAP, R.T.; (b) (CO)2Cl, CH2Cl2, R.T.; (c) di-amine, CH2Cl2, R.T.; and (d) NaOH, CH3OH/THF, R.T.