Figure 6 | Scientific Reports

Figure 6

From: Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

Figure 6

The combination of 2-DG and UA-4 effectively inhibits tumor growth in H22 tumor-bearing mice.

a, photographs of vehicle-treated or drug-treated H22 tumor-bearing mice with representative tumors. Photographs were taken at 7 and 14 days after compounds treatment. The bottom images show tumor volume of the groups at 14 days. Tumor volume (b) and mice weight (c) were measured every other day. After 14 days, inhibition rate (d) and tumor weight (e) were quantitatively analyzed. f, histological examinations; tumors were analyzed by hematoxylin and eosin staining for histological features. (*p < 0.05, **p < 0.01, compared to the control group).

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