Table 2 Heat capacity changes and change in the solvent-accessible surface area for the duck Na,K-ATPase binding to AMP, ADP and ATPa

From: Critical role of γ-phosphate in structural transition of Na,K-ATPase upon ATP binding

Ligand

ΔCp, cal·mole−1·K−1

ΔAtot_minb, Å2

ΔAtot_maxb, Å2

AMP

−66

349

551

ADP

−43

228

333

ATP

−760

4021

5891

  1. aHeat capacity changes were obtained as d(ΔH)/dT from Figure 2.
  2. bChanges in solvent-accessible surface area were estimated using the following formula: ΔCp = k × ΔAtot, where ΔAtot is the total change in solvent accessible surface area in Å2. ΔAtot_max and ΔAtot_min are calculated for the min and max k values (0.129 and 0.189 cal/(K·mol·Å2), as shown in21).
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