Table 1 CASTp analysis confirmed of α2u– globulin binding pockets. The table shows the area and volumes of the 13 pockets found by CASTp. Locations of pockets with significant volumes are indicated
aPocket | bArea,Å2 | cVolume, Å3 | dColor | eAmino acid residues with position |
|---|---|---|---|---|
1 | 361.7 | 461 | green | Met38, Val40, Met42, Phe54,Phe56, Leu69, Ala71, Val82, Tyr84, Asn88, phe90, Phe103, Leu105, Met117,Val118, Tyr120 |
2 | 214 | 185.6 | blue | Glu34, Asn35, Gly36, Arg39, Phe41,Ile58, Lys59, Gly62, Thr154,Asp155 |
3 | 127.1 | 23.8 | cyan | Phe20, Ser21, Phe41, Met42, Gln43, Arg57, Arg156, Leu158 |
4 | 92.7 | 91.3 | yellow | Lys28, Lys31, Asp85, Asn107, Lys109, Glu112, Thr113, Phe114 |
5 | 40.1 | 33.4 | magenta | Thr89, Phe90, Thr91, His104, Ile106 |
6 | 41.5 | 24.1 | pink | Ser21, Ile22, Val23, Val24, Val118, Leu119, Tyr120 |
7 | 32.5 | 22 | purple | Asn27, Asn27, Lys28, Phe114, Gln115 |
9 | 25.5 | 13.9 | brown | Thr74, Glu79, Glu79, Tyr80, Thr89 |
10 | 39.2 | 22.3 | gold | Ser21, Val24, Val40, Val118, Tyr120 |
11 | 32.4 | 17.1 | violet | Leu15, Ile45, Leu52, Phe03 |
12 | 26.4 | 12.5 | hotpink | His44, Asp46, Gly53, Tyr68 |
13 | 10.8 | 6.8 | goldenrod | Arg99, Tyr100, Ile130, Lys133 |
