Table 2 Risk estimates of CART terminal nodes

From: The Roles of Ca2+/NFAT Signaling Genes in Kawasaki Disease: Single- and Multiple-Risk Genetic Variants

Node

Genotype

KD cases

Controls

Case rate* (%)

OR

95% CI

LR P

1

rs2720378 (W)

185 (43.22)

253 (51.32)

42.2

Ref.

Ref.

 

3

rs2720378 (HV)-rs2069762 (W)

91 (21.26)

117 (23.73)

43.8

1.06

0.76–1.48

0.718

5

rs2720378 (HV)-rs2069762 (HV)-rs1561876 (HV)

56 (13.08)

61 (12.37)

47.9

1.26

0.83–1.89

0.276

6

rs2720378 (HV)-rs2069762 (HV)-rs1561876 (W)

96 (22.43)

62 (12.58)

60.8

2.12

1.46–3.07

<0.001

  1. Abbreviations: CART, classification and regression tree; KD, Kawasaki disease; OR, odds ratio; 95%CI, 95% confidence interval; LR, logistic regression; W, wild type homozygote; H, heterozygote; V, variant homozygote
  2. *Case rate is the percentage of KD patients among all individuals in each node
  3. ORs of terminal nodes were calculated by LR analysis adjusted for gender
  4. All the P values were adjusted for gender. The positive results were in bold