Figure 4
Correlation analysis of the 7 TCM prescriptions and known compounds.
The weighted uncentred Pearson's correlation coefficient between each compound and each prescription was calculated. The X axis denotes the 7 TCM prescriptions and the Y axis denotes the compounds. The upper dendrogram was conducted with hierarchical clustering. In the left, the chemical names are coloured according to the activity code annotations. For example, serotonin signalling is labelled grey. Compounds associated with different neural pathways are labelled in different colours. However, there is an exception in the last colour block, which includes two classical antidepressants that did not belong to a neural signalling pathway. In the colour bar, red indicates a high correlation and blue indicates a low correlation.
