Table 2 Results of Haplotype Association Analysis

From: Novel common variants and susceptible haplotype for exfoliation glaucoma specific to Asian population

Haplotypes

SNP allelesa

Freq. in XFS/XFG

Freq. in controls

Chi-square

P-valuesb

 

OMNIBUS

NA

NA

122.4

9.57 × 10−25

H1

GGA

0.0039

0.1294

31.9

1.62 × 10−8

H2

GTA

0.0043

0.0407

7.7

0.0055

H3

AGG

0.0176

0.0835

12.2

0.0005

H4

GGG

0.0125

0.1517

33.4

7.55 × 10−9

H5

ATG

0.0319

0.0675

3.9

0.0471

H6

GTG

0.9297

0.5272

118.5

1.33 × 10−27

  1. aHaplotypes were constructed with the SNPs in the following order: rs16958445, rs1048661 and rs3825942.
  2. bP values were calculated by use of the ‘hap-assoc’ option of PLINK.
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