Figure 3
From: Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique
Characterization of Nor iPSCs after gene manipulation Immunofluorescence staining of the “Nor” iPS cells (a/b/c) and the “AP” iPS cells (d/e/f) revealed expression of the pluripotency-specific markers Nanog (red) and TRA-1-81 (green) in vitro. Hematoxylin and eosin staining of teratoma sections of NOD-SCID mice were generated from the “Nor” (g/h/i/j) and “AP” cell lines (k/l/m/n).
