Figure 1 | Scientific Reports

Figure 1

From: 3′UTR shortening identifies high-risk cancers with targeted dysregulation of the ceRNA network

Figure 1

Bayesian change point approach for APA analysis with exon array data.

(a) Mapping of exon array probes to ZEB2 3′UTR. (b) BCP analysis results. The upper panel shows the input probe intensities (dots) and posterior probe mean intensities (solid lines) for all samples. The lower panel shows the posterior change point probabilities for the probes. (c) The correlation coefficient between gene expression and 3′UTR shortening follows a bimodal distribution. The histogram represents the distribution of the correlation coefficient (blue). The estimated densities are shown for individual (magenta) and combined (turquoise) distributions.

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