Figure 6
From: Baicalin, a metabolite of baicalein with antiviral activity against dengue virus
Effect of baicalin against DENV-2 cell attachment.
Foci forming unit reduction assay (FFURA) was performed to evaluate the anti-attachment activity of baicalin against DENV attachment to the Vero cells. Anti-attachment activity of 50 μg/ml of baicalin (B); or with 25 μg/ml of baicalin (C) or without baicalin (D) using DENV foci immunostaining method on the day 4 post infection were shown. Up to 50 μg/ml of baicalin used in this test and it was shown that the highest concentration of the baicalin can inhibit the DENV-2 cell attachment significantly (A). Data from triplicate assays for three independent experiments were plotted using Graph Pad Prism Version 5 (Graph Pad Software Inc., San Diego, CA.).
