Figure 3 | Scientific Reports

Figure 3

From: Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β

Figure 3

Immunohistochemistry and real-time qPCR analyses of adhesion molecule expression in venous malformations (VMs).

(A, C) In normal skin (SK) tissues, VE-Cadherin and N-Cadherin are strongly expressed around the blood vessels. However, their expression levels are remarkably downregulated in VM tissues. (B, D) Quantification of the mRNA expression levels of VE-Cadherin and N-Cadherin in VM and SK tissues. Data are expressed as means ± SD for qPCR. ***, P < 0.001 versus SK tissues.

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