Figure 7

Immunohistochemistry and real-time qPCR analyses to determine TGF-β expression in venous malformations (VMs).
(A) TGF-β is downregulated in VM tissues when compared with normal skin (SK) tissues. (B) Quantification of TGF-β immunoreactivity in VM and SK tissues. (C) Quantification of the mRNA expression level of TGF-β in VM and SK tissues. Data are expressed as means ± SEM for histoscore and means ± SD for qPCR. ***, P < 0.001 versus SK tissues.