Figure 3
From: Developing Hypothetical Inhibition Mechanism of Novel Urea Transporter B Inhibitor
Activity of inhibitors against UT-B in human, rat and mouse.
(a) Dose-dependent inhibition activity for PU21, determined by the osmotic lysis assay in human,rat and mouse erythrocytes. (b) Dose-dependent inhibition activity for PU168. (c) Dose-dependent inhibition activity for PU468. (d) Dose-dependent inhibition activity for PU474. Mean ± s.e.m., n = 3.
