Figure 4
From: Developing Hypothetical Inhibition Mechanism of Novel Urea Transporter B Inhibitor
Binding pose of (a) PU168, (b) PU21, (c) PU468, (d) PU474 in the UT-B predicted binding site.
Rigid docking pose provides details of the functional group-residue interactions and insights into residue mutation. The hydroxyl group of PU21 can interact with ASN289 inside the binding pocket whereas PU168, PU468 and PU474 cannot.
