Figure 4
From: The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA Repair
IR-induced Rad51 foci formation is impaired by the BRCA1 K898E mutation.
(a) Images of IR-induced Rad51 foci in transfected 780 cells. Scale bar: 10 μm. (b) The percentage of transfected 780 cells with 5 or more Rad51 foci. Results are presented as mean ± SEM of at least three independent experiments. *** P < 0.001.
