Figure 7

The scheme of mechanisms enhancing DR5 expression by sulindac sulfide.
Sulindac sulfide increases MZF1. The transcription factor MZF1 then upregulates DR5 promoter activity through its binding site.

The scheme of mechanisms enhancing DR5 expression by sulindac sulfide.
Sulindac sulfide increases MZF1. The transcription factor MZF1 then upregulates DR5 promoter activity through its binding site.