Figure 5

Down-regulation of Oct-1 in prion-infected materials.
The endogenous Oct-1 expression was examined in N2a58 and ScN2a58 cells (a) and in the uninfected and 22 L prion-infected ddY mice brains (Un-Br and 22L-Br) (b). The amount of Oct-1 was analyzed by immunoblotting. Each β-actin was used as a loading control. Quantification results were shown on bottom of WB panels, respectively. P values were determined by Student's-t test.