Table 2 Genes with somatic mutation rates significantly higher than background

From: Exome sequencing identifies frequent mutation of MLL2 in non–small cell lung carcinoma from Chinese patients

Gene Symbol

NO. of Mutations

Gene Length

P value-FCPT

P value-LRT

P value-CT

TP53

5

2261

1.68E-05

4.96E-08

1.14E-08

MLL2

5

18074

2.66E-03

2.57E-06

1.76E-05

NEK1

2

4366

2.92E-02

6.17E-06

1.12E-04

OR52A1

2

942

7.72E-03

9.85E-06

4.23E-06

IGSF11

3

2739

1.50E-02

3.66E-05

3.76E-05

BBS7

2

2395

3.59E-02

1.08E-04

5.60E-05

PAPPA2

3

7061

4.19E-02

1.79E-04

2.51E-04

CDH10

3

4036

2.46E-02

5.53E-04

9.03E-05

TTN

13

138148

1.21E-03

6.61E-04

4.48E-05

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