Table 1 Clinical characteristics of miR-198 expression by in situ hybridization

From: MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8

Clinical characteristics

 

Total miR-198 expression

 
 

Low

%

High

%

P-value *

Gender

 

Male

60

34

56.67

26

43.33

0.887

Female

56

31

55.36

25

44.64

 

Age (years)

 

<60

22

15

68.18

7

31.82

0.202

≥60

94

50

53.19

44

46.81

 

Tumor size (cm3)

 

<40

69

35

50.72

34

49.28

0.162

≥40

47

30

63.83

17

36.17

 

Histological grade

 

I, I–II, II

81

38

46.91

43

53.09

0.003*

II–III, III

35

27

77.14

8

22.86

 

Tumor status (T)

 

T1–T2

22

7

31.82

15

68.18

0.010*

T3–T4

94

58

61.70

36

38.30

 

Lymph node metastasis (N)

 

N0

82

39

47.56

43

52.44

0.004*

N1–N3

34

26

76.47

8

23.53

 

Distal metastasis status (M)

 

M0

114

63

55.26

51

44.74

0.311

M1

2

2

100

0

0

 

AJCC stage

 

1–2

80

37

47.25

43

53.75

0.002*

3–4

36

28

77.78

8

22.22

 
  1. Samples with downregulated miR-198 expression detected by ISH showed a significant association with histological grade (P = 0.003), tumor status (P = 0.01), AJCC stage (P = 0.002) and lymph node invasion (P = 0.004).
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