Figure 3
From: Critical limitations of consensus clustering in class discovery
CC shows stable clusters in a simulated dataset (Sim25) that carries gene-gene correlation but lacks known clusters.
(a) sample-sample correlation heatmaps, showing weak or inconsistent clustering, (b) 80% gene-subsampling consensus heatmaps, (c) 80% sample-subsampling consensus heatmaps. Sim25 is chosen as a representative random dataset from the pcNormal null distribution. For each K in 2–5 (show from left to right), the order of samples on all three heatmaps is the one obtained from average-linkage hierarchical clustering on the gene-subsampling consensus matrix (in b).
