Figure 4
From: Stiff substrates enhance cultured neuronal network activity
Effects of substrate stiffness on spontaneous EPSC and IPSC.
(a) Representative recordings of spontaneous EPSC from DIV14–18 neurons in soft and stiff substrates. (b) Cumulative distribution and amplitude of spontaneous EPSC. (c) Cumulative distribution of inter-event intervals and frequency of spontaneous EPSC. (d) Representative recordings of spontaneous IPSC from DIV14–18 neurons in soft and stiff substrates. (e) Cumulative distribution and amplitude of spontaneous IPSC. (f) Cumulative distribution of inter-event intervals and frequency of spontaneous IPSC. *, p < 0.05 denote significant difference and NS, no significant difference. The numbers shown in parenthesis indicate neurons examined in each case.
