Figure 3

Heat maps of structural classes versus FXR activity.
Each hexagon represents a cluster of structurally similar compounds. Clusters are annotated with a (x,y) coordinate and colored according to the enrichment of FXR actives [−log(p-value)] in the cluster. Warmer colors indicate higher enrichment of FXR actives and colder colors indicates less significant enrichment of FXR actives. Empty clusters are colored in white.