Table 2 The association of miR-3127-5p expressiona with Ki-67, p53, c-Abl and EGFR immunohistochemistry staining in 177 cases of NSCLC

From: Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway

  

miR-3127-5p

IHC

# of cases

   Ct median(IQR)

p value

Ki-67

177

  

(-)

43

16.21(11.32–22.98)

 

(+)

134

12.78(7.76–16.76)

0.002b

p53

177

  

(-)

78

13.92(10.70–17.99)

0.28b

(+)

99

12.96(7.49–19.54)

 

EGFR

177

  

(-)

83

13.66(8.50–19.74)

0.15b

(+)

94

11.79(8.05–16.93)

 

c-Abl

177

  

(-)

102

13.92(10.97–21.03)

0.003c

(+)

38

13.40(7.94–17.29)

 

(++)

30

9.55(5.94–14.91)

 

(+++)

7

8.12(7.48–14.18)

 
  1. aLevel of miRNA expression ranged from no detectable expression ( ) to very high levels of expression (+++).
  2. bWilcoxon Mann Whitney test.
  3. c Kruskal-Wallis H tests.
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