Figure 5 | Scientific Reports

Figure 5

From: In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance

Figure 5

Molecular-scale mechanism of ineffective Her2 population.

A) Resistant clones (H6 and C5) overexpress MUC4 while sensitive clones (E8 and C11) do not. B) Dual-staining of Her2 and MUC4 in one single cell showing negative co-localization for Her2 and MUC4. Similar features were observed in multiple cells, but only a representative one was shown here. Scale bars, 50 μm.

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