Figure 3
From: Relevance of LIG4 gene polymorphisms with cancer susceptibility: Evidence from a meta-analysis
(A): The required information size to demonstrate the relevance of rs1805388 gene polymorphisms with cancer susceptibility; (B): The required information size to demonstrate the relevance of rs1805388 gene polymorphisms with risk of cancer among Caucasians. The solid blue line is the cumulative Z-curve. The dashed inward-sloping line to the left represents the trial sequential monitoring boundaries.
