Figure 13 | Scientific Reports

Figure 13

From: Cancer-driven dynamics of immune cells in a microfluidic environment

Figure 13

Left panels: angular correlation function CWT(τ) of the turning angle θ of WT-PRE splenocytes (upper panel) and of WT-POST splenocytes (lower panel).

Each turn occours every 4 minutes. In both cases the correlation is mostly positive, meaning that the process has memory. In the inset we show the polar histogram of the angle measured with respect to the horizontal axis. Right panels: distribution of the turning angle for WT-PRE splenocytes (upper panel) and of WT-POST splenocytes (lower panel). The experimental distribution is fitted by a Gaussian peaked at 0 rad, since splenocytes tend to maintain the same direction. Note that the resulting Gaussian shape is in full agreement with the mathematical description of the motion in terms of a (biased and uncorrelated) stochastic process (further an analysis of its variance will be successfully exploited in the last section due to numerical simulations).

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